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GrpEL Antibodies

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un sistema unico per la rapida identificazione del GrpEL Antibodies. Evidenziare i nomi dei prodotti sulla tabella per vedere i dati rappresentativi per ciascun prodotto.

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NOME DEL PRODOTTOCodice del prodotto ISOTOPOEPITOPOAPPLICAZIONISPECIECITAZIONIVALUTAZIONE
GrpEL1 (D-15)sc-242966capra IgGInternal (h)WB, IP, IF, ELISAm, r, hNEW
GrpEL2 (P-13)sc-164555capra IgGInternal (h)WB, IP, IF, ELISAm, r, h, e, c, b
GrpEL2 (T-14)sc-164556capra IgGN-terminal (h)WB, IF, ELISAm, r, hNEW
GrpEL2 (Y-14)sc-164557capra IgGInternal (h)WB, IP, IF, ELISAm, r, h

GrpEL CRISPR/Cas9 Knockout Plasmids include:

NOME DEL PRODOTTOCodice del prodotto APPLICAZIONISPECIECITAZIONI
GrpEL2 CRISPR/Cas9 KO Plasmid (h)sc-408498gene knockoutumanoNEW
GrpEL1 CRISPR/Cas9 KO Plasmid (h)sc-413374gene knockoutumanoNEW
GrpEL1 CRISPR/Cas9 KO Plasmid (m)sc-421728gene knockouttopoNEW
GrpEL2 CRISPR/Cas9 KO Plasmid (m)sc-421729gene knockouttopoNEW

GrpEL silenziatori genici siRNA, plasmidi shRNA e particelle lentivirali shRNA includono:

siRNAPlasmidi shRNA Particelle lentivirali shRNA CITAZIONICLASSIFICA
GrpEL1 siRNA (h): sc-89323GrpEL1 shRNA Plasmid (h):
sc-89323-SH
GrpEL1 shRNA (h)
Particelle lentivirali:sc-89323-V
Not Yet Rated
GrpEL1 siRNA (m): sc-145781GrpEL1 shRNA Plasmid (m):
sc-145781-SH
GrpEL1 shRNA (m)
Particelle lentivirali:sc-145781-V
Not Yet Rated
GrpEL2 siRNA (h): sc-91628GrpEL2 shRNA Plasmid (h):
sc-91628-SH
GrpEL2 shRNA (h)
Particelle lentivirali:sc-91628-V
Not Yet Rated
GrpEL2 siRNA (m): sc-145782GrpEL2 shRNA Plasmid (m):
sc-145782-SH
GrpEL2 shRNA (m)
Particelle lentivirali:sc-145782-V
Not Yet Rated

GrpEL2 (GrpE protein homolog 2) is a 225 amino acid mitochondrial matrix protein and component of the PAM complex. Consisting of Tim44, Tim14, HSP 70, Magmas, GrpEL1 and GrpEL2, the PAM complex plays an essential role in the ATP-dependent translocation of transit peptide-containing proteins to the mitochondrial matrix from the inner membrane. GrpEL2 regulates the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins and stimulates its ATPase activity. The gene encoding GrpEL2 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.