epitope mapping within an internal region of ZBED4 of human origin
recommended for detection of ZBED4 of mouse, rat and human origin by WB, IP, IF and ELISA; non cross-reactive with ZBED2; also reactive with additional species, including equine, canine and avian
TransCruz reagent for Gel Supershift and ChIP applications, sc-86942 X, 200 µg/0.1 ml
ZBED4 Background Information The zinc finger BED domain-containing protein family (ZBED) is comprised of ZBED1, ZBED2, ZBED3, ZBED4 and ZBED5. They each contain one BED-type zinc finger domains with the exception of ZBED4, which contain 4 BED-type zinc finger domains. ZBED1 is thought to function as a transcription factor that regulates a number of ribosomal protein (RP) encoded genes by binding specifically to 5'-TGTCG[CT]GA[CT]A-3' DNA regions found in RP promotors. ZBED3 is an Axin-binding protein involved in Wnt/beta-catenin signaling modulation. ZBED4 expression has been shown in human and mouse retinas where it is thought to act as a regulatory protein in cone photoreceptors and Müller cells. The functions of ZBED2 and ZBED5 have yet to be elucidated.
ZBED4 (N-18)
Clicca sull'immagine per ingrandirla
ZBED4 (N-18): sc-86942. Western blot analysis of ZBED4 expression in HeLa whole cell lysate.
