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- mouse monoclonal IgG1, 50 µg/0.5 ml
- raised against a synthetic peptide corresponding to Raptor of human origin
- recommended for detection of Raptor of mouse, rat and human origin by WB and IP; also reactive with additional species, including canine
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Informazioni ordiniCitazioni prodotti
Recommended Support Products:
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| Specie |
Nome del gene |
Codice del gene |
Locus cromosoma |
Isoform (mRNA) Accession # |
codice accesso proteina |
Numero d'ordine |
| Umano |
KIAA1303 |
57521 |
17q25.3 |
NM_020761 |
Q8N122
|
607130 |
| Mouse |
4932417H02Rik |
74370 |
11 E2 |
|
Q8K4Q0
|
N/A |
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Raptor Background Information
Regulatory associated protein of FRAP, also designated Raptor, is a binding partner for mammalian target of rapamycin kinase (FRAP), and is essential for FRAP signalling in vivo. Raptor binding to FRAP is critical for FRAP-catalysed substrate phosphorylation of 4E-BP1. The raptor-FRAP complex is nutrient-sensitive and is important for a mechanism by which cells coordinate cell growth and size with changing environmental conditions. Raptor serves as a negative regulator of FRAP kinase activity under nutrient-deprived conditions and is an important component in the FRAP pathway. Raptor is highly expressed in skeletal muscle and to a lesser extent in brain, kidney, lung and placenta.
| Raptor (10E10) Citazioni prodotti |
Visualizza come altri ricercatori hanno utilizzato l'anticorpo Raptor (10E10): sc-81537 e/o i coniugati per l'anticorpo Raptor (10E10).
3 total citations Loading citations.
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Raptor (10E10)
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Raptor (10E10): sc-81537. Western blot analysis of Raptor expression in serum starved HeLa (A), Hep G2 (B), HEK293 (C), SH-SY5Y (D), MDCK (E), PC-12 (F), CMT 93 (G), Neuro 2A (H) and 3T3 (I) whole cell lysates.
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