epitope mapping at the N-terminus of TAF I p68/63 of human origin
recommended for detection of TAF I p63 of human origin and TAF I p68 of mouse and rat origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
blocking peptide, sc-6574 P
TransCruz reagent for Gel Supershift and ChIP applications, sc-6574 X, 200 µg/0.1 ml
TAF I p68/63 Background Information For gene transcription governed by RNA polymerase I, the human transcription factor SL1 (mouse TIF-IB) directs the assembly of initiation complexes at the prompter. Like TFIID, which directs transcription by RNA polymerase II, SL1/TIF-IB contains the TATA-binding protein (TBP) and a set of TBP-associated factors (TAFs). The three TAF I subunits, hTAF I p110, hTAF I p63 and hTAF p48 (or mouse TAF I p95, TAF I p68 and TAF I p48) are all integral components of SL1/TIF-IB. The mutually exclusive binding of either TAF I or TAF II subunits to TBP is believed to direct the formation of promoter- and RNA polymerase-specific complexes.
TAF I p68/63 (N-15) Citazioni prodotti
Visualizza come altri ricercatori hanno utilizzato l'anticorpo TAF I p68/63 (N-15): sc-6574 e/o i coniugati per l'anticorpo TAF I p68/63 (N-15).
