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- mouse monoclonal IgG2b, 200 µg/ml
- raised against stimulated leukocytes of human origin
- recommended for detection of ICAM-3 of human origin by WB, IP, IF, IHC(P) and FCM
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Informazioni ordini
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| Specie |
Nome del gene |
Codice del gene |
Locus cromosoma |
Isoform (mRNA) Accession # |
codice accesso proteina |
Numero d'ordine |
| Umano |
ICAM3 |
3385 |
19p13.2 |
NM_002162 |
P32942
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146631 |
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ICAM-3 Background Information Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth. These proteins are thought to play an important role in embryogenesis and development. ICAM-3, also designated CD50 and ICAM-R, is a type I membrane protein that is thought to regulate morphological changes during cell locomotion. ICAM-3 acts as a counter-receptor for the leukocyte Integrin aL/b2, and is known to activate T cells and polymorphonuclear leukocytes. ICAM-3 also binds to Moesin, via the cytoplasmic domain of ICAM-3. The expression
of ICAM-3 is induced by RANTES, a chemoattractant known to activate T lymphocytes. ICAM-3 is also a major ligand for the leukocyte Integrin LFA-1 (CD11a/CD18). |
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ICAM-3 (186.2G9)
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ICAM-3 (186.2G9): sc-65269. Indirect FCM analysis of human peripheral blood leukocytes stained with ICAM-3 (186.2G9), followed by PE-conjugated goat anti-mouse IgG: sc-3738. Black line histogram represents the isotype control, normal mouse IgG 2b: sc-3879.
ICAM-3 (186.2G9): sc-65269. Western blot analysis of ICAM-3 expression in human PBL (A), Ramos (B), NAMALWA (C) and Jurkat (D) whole cell lysates.
ICAM-3 (186.2G9): sc-65269. Western blot analysis of ICAM-3 expression in Jurkat (A), U-698-M (B), U-937 (C), HuT 78 (D) and Ramos (E) whole cell lysates.
ICAM-3 (186.2G9): sc-65269. Western blot analysis of ICAM-3 expression in non-transfected 293T: sc-117752 (A), human ICAM-3 transfected 293T: sc-116577 (B) and human PBL (C) whole cell lysates.
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