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- goat polyclonal IgG, 200 µg/ml
- epitope mapping near the C-terminus of γ-catenin of human origin
- recommended for detection of γ-catenin of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
- blocking peptide, sc-30997 P
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γ-catenin Background Information
The catenins, å, ∫ and ©, are proteins which bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. å-catenin was initially described as an E-cadherin associated protein, and since has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. ∫-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. ∫-catenin has also been found in complexes with the tumor suppressor protein APC. ©-catenin, also known as plakoglobin, binds with å-catenin and N-cadherin. It has been shown that the transmembrane phosphatase PTPµ associates with catenin/cadherin complexes and may regulate complex signaling.
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Visualizza come altri ricercatori hanno utilizzato l'anticorpo γ-catenin (K-20): sc-30997 e/o i coniugati per l'anticorpo γ-catenin (K-20).
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γ-catenin (K-20)
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γ-catenin (K-20): sc-30997. Western blot analysis of γ-catenin expression in non-transfected 293T: sc-117752 (A), human γ-catenin transfected 293T: sc-159343 (B) and A-431 (C) whole cell lysates. γ-catenin (K-20): sc-30997. Western blot analysis of γ-catenin expression in A-431 whole cell lysate.
γ-catenin (K-20): sc-30997. Western blot analysis of γ-catenin expression in A-431 whole cell lysate.
γ-catenin (K-20): sc-30997. Western blot analysis of γ-catenin expression in HeLa whole cell lysate.
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