NAT-10 Background Information NAT-10 (N-acetyltransferase 10) is a nuclear protein that belongs to the UPF0202 family. It has a single N-acetyltransferase domain that likely functions as a histone acetyltransferase. NAT10 functions primarily to regulate the activity of telomerase. It is upregulated in response to DNA damage and is likely to take part in genotoxic resistance and DNA repair. NAT-10 has a high binding potential for the promoter region of TERT which stimulates the production of telomerase. These varieties of function imply that human telomerase complexes have multiple functions rather than specific duties.
NAT-10 (B-4)
Clicca sull'immagine per ingrandirla
NAT-10 (B-4): sc-271770. Western blot analysis of NAT-10 expression in HeLa nuclear extract.
NAT-10 (B-4): sc-271770. Immunofluorescence staining of methanol-fixed HeLa cells showing nucleolar and nuclear localization.
