raised against a peptide mapping within an internal region of NAT-10 of human origin
recommended for detection of NAT-10 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
NAT-10 Background Information NAT-10 (N-acetyltransferase 10) is a nuclear protein that belongs to the UPF0202 family. It has a single N-acetyltransferase domain that likely functions as a histone acetyltransferase. NAT10 functions primarily to regulate the activity of telomerase. It is upregulated in response to DNA damage and is likely to take part in genotoxic resistance and DNA repair. NAT-10 has a high binding potential for the promoter region of TERT which stimulates the production of telomerase. These varieties of function imply that human telomerase complexes have multiple functions rather than specific duties.
NAT-10 (D-5)
Clicca sull'immagine per ingrandirla
NAT-10 (D-5): sc-271142. Immunofluorescence staining of methanol-fixed HeLa cells showing nucleolar and nuclear localization.
NAT-10 (D-5): sc-271142. Western blot analysis of NAT-10 expression in non-transfected: sc-117752 (A) and mouse NAT-10 transfected: sc-127198 (B) 293T whole cell lysates.
NAT-10 (D-5): sc-271142. Western blot analysis of NAT-10 expression in PMA treated Jurkat whole cell lysate.
