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- rabbit polyclonal IgG, 200µg/ml
- epitope corresponding to phosphorylated of β2-AR of human origin
- recommended for detection of Ser 355 and Ser 356 dually phosphorylated β2-AR of human origin by WB, IP, IF and ELISA
- blocking peptide, sc-22191 P
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p-β2-AR Background Information ∫2 adrenergic receptors (∫2-ARs) bind catecholamines (epinephrine and norepinephrine) and influence development, behavior, cardiac function, smooth muscle tone, and metabolism. ∫2-AR signaling complexes can contain class C L-type calcium channel CaV1.2, G protein, adenylyl cyclase, cAMP-dependent kinase and PP2A phosphatase. ∫2-ARs are present in adipose, blood, lung, brain, heart, nose, pancreas, skeletal muscle, skin and vessels. Phosphorylation of Ser 345/346 and Ser 355/356 by PKA and GRK, respectively, promotes desensitization of the ∫2-AR.
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Visualizza come altri ricercatori hanno utilizzato l'anticorpo p-β2-AR (Ser 355/ Ser 356)-R: sc-22191-R e/o i coniugati per l'anticorpo p-β2-AR (Ser 355/ Ser 356)-R.
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p-β2-AR (Ser 355/ Ser 356)-R
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p-β 2-AR (Ser 355/ Ser 356): sc-22191. Western blot analysis of β 2-AR phosphorylation in HeLa whole cell lysate.
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