Peroxynitrite scavenger. Potent inhibitor of mouse inducible nitric oxide synthase (iNOS; NOS II).
For Research Use Only
Referenze
Spontaneous rearrangement of aminoalkylisothioureas into mercaptoalkylguanidines, a novel class of nitric oxide synthase inhibitors with selectivity towards the inducible isoform: G.J. Southan, et al.; Br. J. Pharmacol. 117, 619 (1996)
Pharmacological characterization of guanidinoethyldisulphide (GED), a novel inhibitor of nitric oxide synthase with selectivity towards the inducible isoform: C. Szabo, et al.; Br. J. Pharmacol. 118, 1659 (1996)
The iNOS inhibitor and peroxynitrite scavenger guanidinoethyldisulfide (GED) prevents onset of type I diabetes in two animal models: G.J. Southan, et al.; Acta Physiol. Scand. 167 Suppl., O-35 (1999)
The combined inducible nitric oxide synthase inhibitor and free radical scavenger guanidinoethyldisulfide prevents multiple low-dose streptozotocin-induced diabetes in vivo and interleukin-1beta-induced suppression of islet insulin secretion in vitro: J.G. Mabley, et al.; Pancreas 28, E39 (2004)
