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3-Bromo-7-nitroindazole sodium salt: sc-220856

 |  Scheda tecnica  | MSDS
  • Specifications
    • Offered as 5 mg (sc-220856)
    • Peso molecolare: 264
    • Molecular Formula: C7H3BrN3NaO2
    • Physical Appearance: Red solid
    • Solubility: Soluble in DMSO or methanol
    • SMILES: C1=CC2=C(C(=C1)[N+](=O)[O-])[N-]N=C2Br.[Na+]
  • Descrizione
    • Salt form of 3-bromo-7-nitroindazole. Strong inhibitor of rat cerebellar nitric oxide synthase (nNOS/NOS I). Stronger than 7-nitroindazole
  • For Research Use Only
  • Reference Numbers
  • Referenze
    • 7-Nitro indazole derivatives are potent inhibitors of brain, endothelium and inducible isoforms of nitric oxide synthase: P.A. Bland-Ward & P.K. Moore; Life Sci. 57, PL131 (1995) Evidence for involvement of the neuronal isoform of nitric oxide synthase during induction of long-term potentiation and long-term depression in the rat dentate gyrus in vitro: J. Wu, et al.; Neuroscience 78, 393 (1997) Further in vivo studies on attenuating morphine withdrawal: isoform-selective nitric oxide synthase inhibitors differ in efficacy: D.B. Vaupel, et al.; Eur. J. Pharmacol. 324, 11 (1997) 3-bromo-7-nitroindazole, a neuronal nitric oxide synthase inhibitor, impairs maternal aggression and citrulline immunoreactivity in prairie voles: S.C. Gammie, et al.; Brain Res. 870, 80 (2000) Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism: C.S. Raman, et al.; Biochemistry 40, 13448 (2001) Effects of selective neuronal nitric oxide synthase inhibition on sleep and wakefulness in the rat: M. Cavas & J.F. Navarro; Prog. Neuropsychopharmacol. Biol. Psychiatry 30, 56 (2006)
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3-Bromo-7-nitroindazole sodium salt sc-220856 5 mg $23
3-Bromo-7-nitroindazole sodium salt
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3-Bromo-7-nitroindazole sodium salt
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