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- Specifications
- Offered as 10 mg (sc-202985) and 50 mg (sc-202985A) sizes
- CAS Number: 148819-94-7
- Peso molecolare: 315.38
- Molecular Formula: C14H16KN2O4
- Purity: ≥98%
- Physical Appearance: Blue solid.
- Solubility: Soluble in 100% ethanol, methanol, DMSO or dimethyl formamide. Highly soluble in water or aqueous buffers, e. g. PBS, pH 7.2.
- SMILES: CC1(C([N+](=C(N1[O])C2=CC=C(C=C2)C(=O)[O-])[O-])(C
)C)C.[K+]
- Descrizione
- Carboxy-PTIO, potassium salt is shown to be a stable imidazolineoxyl N-oxide radical compound. Studies have indicated that this agent is a nitric oxide antagonist and as a result causes concentration-dependent reductions of murine aortic relaxation. Further studies suggest that at concentrations of 300μM or more Carboxy-PTIO actually slightly enhances relaxation elicited by nitrergic nerve stimulation.
- Storage
- Safety
- For Research Use Only
- Reference Numbers
- PubChem Compound ID: 2733502
- MDL Number: MFCD00216153
- Referenze
- 1. Akaike, T., et al. 1993. Biochemistry. 32: 827-832. PMID: 8422387
2. Tsunoda, R., et al. 1994. Eur. J. Pharmacol. 262: 55-63. PMID: 7813579
3. Rand, M.J., et al. 1995. Br. J. Pharmacol. 116: 1906-1910. PMID: 8528578
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Carboxy-PTIO, potassium salt
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