Offered as 100 mg (sc-202931) and 500 mg (sc-202931A) sizes
CAS Number: 1937-19-5
Peso molecolare: 110.55
Molecular Formula: CH6N4•HCl
Physical Appearance: White to off-white solid.
Solubility: Soluble in water.
SMILES: C(=N[H])(N([H])[H])N(N([H])[H])[H].Cl[H]
Descrizione
Irreversible inhibitor of iNOS that displays some selectivity over eNOS and nNOS. Exhibits antioxidant and radioprotective effects in vivo.
For Research Use Only
Referenze
Griffiths et al (1993) Aminoguanidine selectively inhibits inducible nitric oxide synthase. Br.J.Pharmacol. 110 963. Laszlo et al (1995) Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo. Eur.J.Pharmacol. 272 169. Moore and Handy (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 18 204. Huang et al (2009) Aminoguanidine alleviates radiation-induced small-bowel damage through its antioxidant effect. Int.J.Radiat.Oncol.Biol.Phys. 74 237.
