Offered as 100 mg (sc-200353) and 500 mg (sc-200353A) sizes
CAS Number: 25371-96-4
Peso molecolare: 212.2
Molecular Formula: C10H7F3N2
Purity: 98%
Physical Appearance: White solid
Solubility: DMSO (30 mg/ml), dichloromethane (25%), slightly soluble in water (5mg/ml), 0.1 N HCl (6mg/ml), 0.1 N NaOH (2mg/ml) and ethanol
SMILES: FC(F)(F)C1=C(C=CC=C1)N1C=CN=C1
Descrizione
TRIM is an inhibitor of nitric oxide synthase nNOS and iNOS with IC50 values of 28.2 µM and 27.0 µM respectively. Studies involving mice suggest that TRIM is a useful tool in determining the roles of NOS in the central nervous system. In addition, TRIM inhibits acetic acid induced abdominal constriction of mice, thus displaying its antinociceptive ability. Furthermore, TRIM interferes with the binding between arginine and tetrahydrobiopterin.
Storage
Store as supplied at room temperature for up to 1 year.
Store solutions at -20° C for up to 3 months.
For Research Use Only
The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.
