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3-Bromo-7-nitroindazole: sc-200347

 |  Scheda tecnica  | MSDS
  • Specifications
    • Offered as 5 mg (sc-200347) and 25 mg (sc-200347A) sizes
    • CAS Number: 74209-34-0
    • Peso molecolare: 242.03
    • Molecular Formula: C7H4BrN3O2
    • Physical Appearance: Light yellow solid
    • Solubility: Soluble in DMSO (50 mg/ml)
    • SMILES: C1=CC2=C(NN=C2C(=C1)[N+](=O)[O-])Br
  • Descrizione
    • 3-Bromo-7-nitroindazole, is a 7-nitro indazole derivative, that inhibits bovine endothelial, rat lung, and rat cerebellar nitric oxide synthase (NOS) enzyme activity. This compound was also reported to provide significant neuroprotection against ischaemia-induced brain damage in rat models. Experiments suggest that 3-Bromo-7-nitroindazole displays the capacity to prevent effects of MCPG, a metabotropic receptor antagonist. Metabotropic receptors decrease synaptic transmission in murine models.
  • Storage
    • Store at -20° C
  • For Research Use Only
    • The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.
  • Reference Numbers
    • PubChem Compound ID: 1649
  • Referenze
    • 1. Bland-Ward, P.A., et al. 1995. Life Sci. 57: PL131-PL135. PMID: 7544863
      2. O'Neill, M.J., et al. 1997. Brain Res. 760: 170-178. PMID: 9237532
      3. Wada, K., et al. 1998. J. Neurosurg. 89: 807-818. PMID: 9817419
 
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 Informazioni ordini
Nome del prodottoCodice del prodottoUnitàPrezzoQuantitàAggiungiFavorites
3-Bromo-7-nitroindazole sc-200347 5 mg $16
3-Bromo-7-nitroindazole sc-200347A 25 mg $52
3-Bromo-7-nitroindazole
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3-Bromo-7-nitroindazole
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