Offered as 5 mg (sc-200347) and 25 mg (sc-200347A) sizes
CAS Number: 74209-34-0
Peso molecolare: 242.03
Molecular Formula: C7H4BrN3O2
Physical Appearance: Light yellow solid
Solubility: Soluble in DMSO (50 mg/ml)
SMILES: C1=CC2=C(NN=C2C(=C1)[N+](=O)[O-])Br
Descrizione
3-Bromo-7-nitroindazole, is a 7-nitro indazole derivative, that inhibits bovine endothelial, rat lung, and rat cerebellar nitric oxide synthase (NOS) enzyme activity. This compound was also reported to provide significant neuroprotection against ischaemia-induced brain damage in rat models. Experiments suggest that 3-Bromo-7-nitroindazole displays the capacity to prevent effects of MCPG, a metabotropic receptor antagonist. Metabotropic receptors decrease synaptic transmission in murine models.
Storage
Store at -20° C
For Research Use Only
The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.