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- goat polyclonal IgG, 200 µg/ml; also available as rabbit poloclonal IgG, 200 µg/ml, sc-17275-R
- epitope corresponding to a short amino acid sequence containing phosphorylated Tyr 141 of β2 adrenergic receptor of human origin
- recommended for detection of Tyr 141 phosphorylated β2 adrenergic receptor of mouse, rat and human origin WB, IF and ELISA; also reactive with additional species, including equine, canine and avian
- blocking peptide, sc-17275 P
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Informazioni ordini
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| Specie |
Nome del gene |
Codice del gene |
Locus cromosoma |
Isoform (mRNA) Accession # |
codice accesso proteina |
Numero d'ordine |
| Umano |
ADRB2 |
154 |
5q33.1 |
NM_000024 |
P07550
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601665 |
| Mouse |
Adrb2 |
11555 |
18 E1 |
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P18762
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N/A |
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β2-AR Background Information ∫2 adrenergic receptors (∫2-ARs) bind catecholamines (epinephrine and norepinephrine) and influence development, behavior, cardiac function, smooth muscle tone, and metabolism. ∫2-AR signaling complexes can contain class C L-type calcium channel CaV1.2, G protein, adenylyl cyclase, cAMP-dependent kinase and PP2A phosphatase. ∫2-ARs are present in adipose, blood, lung, brain, heart, nose, pancreas, skeletal muscle, skin and vessels. Phosphorylation of Ser 345/346 and Ser 355/356 by PKA and GRK, respectively, promotes desensitization of the ∫2-AR. |
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p-β2-AR (Tyr 141)
Clicca sull'immagine per ingrandirla
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p-β2-AR (Tyr 141)-R: sc-17275-R. Western blot analysis of β2-AR phosphorylation in PMA treated (A) and PMA and lambda protein phosphatase treated (B) HeLa whole cell lysates.
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