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Home » Animal Health » NAT-1/2 (G-5) Antibody: sc-137204

NAT-1/2 (G-5) Anticorpo: sc-137204

 |  Scheda tecnica
  • mouse monoclonal IgG1, 200µg/ml
  • specific for an epitope mapping between amino acids 261-290 at the C-terminus of NAT-1 of human origin
  • recommended for detection of NAT-1 of human origin, NAT-2 of mouse and rat origin and, to a lesser extent, NAT-1 and NAT-3 of mouse and rat origin of mouse, rat and human origin by WB, IP, IF and ELISA
 
Altri NAT Anticorpi ...
 
Informazioni ordini
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Specie Nome del gene Codice del gene Locus cromosoma Isoform (mRNA) Accession # codice accesso proteina Numero d'ordine
Umano NAT1 9 8p22 P18440
 108345
Mouse Nat1 17960 8 B3.3 P50294
 N/A
Mouse Nat2 17961 8 B3.3 NM_008673, NM_010874 P50295
 N/A
Mouse Nat3 17962 8 B3.3 NM_010874 P50296
 N/A
 
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 Informazioni ordini
Nome del prodottoCodice del prodottoUnitàPrezzoQuantitàAggiungiFavorites
NAT-1/2 (G-5) sc-137204 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Nome del prodottoCodice del prodottoUnitàPrezzoQuantitàAggiungiFavorites
NAT-1 siRNA (h) sc-61154 10 µM $258
NAT-1 (h)-PR sc-61154-PR 10 µM $23
 shRNA plasmidi (click product name for more information)
Nome del prodottoCodice del prodottoUnitàPrezzoQuantitàAggiungiFavorites
NAT-1 shRNA Plasmid (h) sc-61154-SH 20 µg $520
 shRNA particelle lentivirali (click product name for more information)
Nome del prodottoCodice del prodottoUnitàPrezzoQuantitàAggiungiFavorites
NAT-1 shRNA (h) Lentiviral Particles sc-61154-V 200 µl $625
 Controllo positivo WB lisati cellulari (click product name for more information)
Nome del prodottoCodice del prodottoUnitàPrezzoQuantitàAggiungiFavorites
NAT-1 (h): 293T Lysate sc-112994 100µg/200µl $205
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
NAT-2 (m): 293T Lysate sc-121945 100µg/200µl $205

NAT-1/2 Background Information
Arylamine N-acetyltransferases (NAT-1 and NAT-2) catalyze N- or O-acetylation of heterocyclic and arylamine substrates in the detoxification of a wide array of drugs. Certain alleles causing high levels of N-acetyltransferase activity have been associated with colon and urinary bladder cancers, as NATs also bioactivate several known carcinogens. Both NAT-1 and NAT-2 are cytoplasmic proteins and play an active role in the detoxification of many arylamine and hydrazine drugs. N-acetylation polymorphism is determined by the level of NAT activity in liver tissues, and has been linked to the action and toxicity of drugs that contain amines. Human NAT-1 is the functional homolog of rodent NAT-2, while human NAT-2 is the functional homolog of rodent NAT-1.
NAT-1/2 (G-5)
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sc-137204
NAT-1/2 (G-5): sc-137204. Western blot analysis of NAT-2 expression in non-transfected: sc-117752 (A) and mouse NAT-2 transfected: sc-121945 (B) 293T whole cell lysates.
sc-137204
NAT-1/2 (G-5): sc-137204. Western blot analysis of NAT-1 expression in non-transfected: sc-117752 (A) and human NAT-1 transfected: sc-112994 (B) 293T whole cell lysates.
sc-137204
NAT-1/2 (G-5): sc-137204. Western blot analysis of NAT-1 expression in non-transfected 293T: sc-117752 (A), human NAT-1 transfected 293T: sc-112994 (B) and HeLa (C) whole cell lysates.
sc-137204
NAT-1/2 (G-5): sc-137204. Western blot analysis of NAT-1/2 expression in HeLa whole cell lysate.
sc-137204
NAT-1/2 (G-5): sc-137204. Western blot analysis of NAT-1/2 expression in Hep G2 whole cell lysate.
sc-137204
NAT-1/2 (G-5): sc-137204. Western blot analysis of NAT-1/2 expression in Hep G2 (A), A-431 (B), A549 (C) and MOLT-4 (D) whole cell lysates.
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