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- goat polyclonal IgG, 200 µg/ml
- epitope mapping at the C-terminus of EGF of rat origin
- recommended for detection of EGF of h, r and, to a lesser extent, mouse origin by WB, IP, IF, IHC(P) and ELISA
- blocking peptide, sc-1343 P
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EGF Background Information
Epidermal growth factor (EGF) is an acid- and heat-stable 53 amino acid protein originally found in rodents and humans. It has been shown to be a potent mitogen for a variety of cell types both in vivo and in vitro. EGF binds to the EGF receptor on the surface of cells and mediates intrinsic phosphorylation of the receptor on tyrosine residues. It has been detected in nearly all body fluids, such as urine (urogastrone), saliva, milk and platelet-rich plasma. EGF, TGFå and vaccinia virus growth factor exhibit 30-40% amino acid homology. Several additional members of the EGF/TGF family have been described; these include Cripto, Amphiregulin and the heparin-binding EGF-like growth factor. Amphiregulin and the heparin-binding EGF-like growth factor both bind to the EGF receptor.
| EGF (R-20) Citazioni prodotti |
Visualizza come altri ricercatori hanno utilizzato l'anticorpo EGF (R-20): sc-1343 e/o i coniugati per l'anticorpo EGF (R-20).
8 total citations Loading citations.
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EGF (R-20)
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EGF (R-20): sc-1343. Western blot analysis of human recombinant EGF fusion protein.
EGF (R-20): sc-1343. Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach tissue showing cytoplasmic staining of glandular cells.
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