IER2 Background Information IER2 (immediate early response protein 2), also known as ETR101, is a 223 amino acid protein belonging to the immediate early response (IER) family. IER proteins are the first gene products to be induced during growth stimulation and/or arrest. IER2 expression can be induced by growth factors,12-O-tetradecanoylphorbol-13-acetate (TPA) or Okadaic acid. The coding region of IER2 contains regions of similarity to the transcription factor proteins that are encoded by the Jun oncogene family, possibly indicating a role for IER2 in transcription regulation. Further evidence for this role includes a GUUUG sequence in the 3’ flanking region of IER2, which is believed to be a mRNA degradation signal similar to those found in transcription regulators.
IER2 (E-19)
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IER2 (E-19): sc-101980. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing nuclear and cytoplasmic staining.
IER2 (E-19): sc-101980. Western blot analysis of IER2 expression in Hep G2 whole cell lysate.
IER2 (E-19): sc-101980. Western blot analysis of IER2 expression in non-transfected 293T: sc-117752 (A), human IER2 transfected 293T: sc-117448 (B) and Hep G2 (C) whole cell lysates.
IER2 (E-19): sc-101980. Western blot analysis of IER2 expression in non-transfected 293T: sc-117752 (A), human IER2 transfected 293T: sc-111654 (B) and Hep G2 (C) whole cell lysates.
IER2 (E-19): sc-101980. Western blot analysis of IER2 expression in non-transfected: sc-117752 (A) and human IER2 transfected: sc-172808 (B) 293T whole cell lysates.
