NOS Activators and Inhibitors

• 1-Amino-2-hydroxyguanidine, p-Toluenesulfonate
  A potent cell-permeable inhibitor of NOS2 (inducible nitric oxide synthase; iNOS), in mouse macrophages and in vitro rat aortic smooth muscle cells (RASM).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-3565	N/A	C8H15N4O4S	10 mg

• 1,3-PB-ITU dihydrobromide
  Potent and selective inhibitor of inducible nitric oxide synthase (iNOS; NOS II).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-220549	N/A	C12H18N4S2•2HBr	10 mg

• 1,3-PBITU, Dihydrobromide
  Competitive and highly potent inhibitor of nitric oxide synthase (NOS) with a stronger selectivity for NOS2 than NOS3.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-3568	N/A	C12H18N4S2··2HBr	50 mg

• 1,4-PB-ITU dihydrobromide
  Potent inhibitor of inducible nitric oxide synthase (iNOS; NOS II).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202003	157254-60-9	C12H18N4S2 ·2HBr	10 mg/50 mg

• 1400 W
  A highly potent and selective inhibitor of inducible nitric-oxide synthase (iNOS).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-3564	214358-33-5	C10H15N3 ·2HCl	5 mg/25 mg

• 2-Amino-4-methylpyridine
  Potent inhibitor of inducible nitric oxide synthase (iNOS; NOS II) both in vitro and in vivo. Analgesic agent.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202879	695-34-1	C6H8N2	1 g

• 2-Imino-4-methylpiperidine acetate
  Specific inhibitor of inducible nitric oxide synthase (iNOS; NOS II).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202402	165383-72-2	C6H12N2 ·C2H4O2	5 mg/25 mg

• 2-Imino-4-methylpiperidine, Acetate
  A strong inhibitor of human iNOS (hNOS II).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-216215	N/A	C8H16N2O2	10 mg

• 2-Imino-4,6-dimethylpiperidine, Acetate
  A strong inhibitor of human iNOS (hNOS II).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-216216	165383-79-9	C9H18N2O2	10 mg

• 2-Iminobiotin
  Reversible inhibitor of mouse inducible and rat neuronal nitric oxide synthase (iNOS/NOS II; nNOS/NOS I).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202403	13395-35-2	C10H17N3O2S	10 mg/50 mg

• 2-Iminopiperidine hydrochloride
  An inhibitor of NO synthases with an IC50 value of 1.0 and selective for iNOS.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-203462	16011-96-4	C5H10N2•HCl	10 mg/50 mg

• 2-Methyl-3,4-dichloropyridine N-Oxide

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-216247	N/A	C6H5Cl2NO	250 mg

• 2,3-Diaminonaphthalene
  Inhibitor of NO formation. DAN reacts rapidly with NO-derived N-nitrosating agent(s) to yield the highly fluorescent product NAT.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202882	771-97-1	C10H10N2	100 mg

• 2,4-Diamino-6-hydroxypyrimidine
  A selective inhibitor of GTP cyclohydrolase I, suppressing biopterin synthesis and inhibiting LPS-induced NO synthesis.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202404	56-06-4	C4H6N4O	250 mg/1g

• 3-Bromo-7-nitroindazole
  A specific inhibitor of nitric oxide synthase (NOS). Has been shown to inhibit bovine endothelial, and rat cerebellar and lung NOS enzyme activity.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-200347	74209-34-0	C7H4BrN3O2	5 mg/25 mg

• 3-Bromo-7-nitroindazole sodium salt
  Salt form of 3-bromo-7-nitroindazole. Strong inhibitor of rat cerebellar nitric oxide synthase (nNOS/NOS I). Stronger than 7-nitroindazole

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-220856	N/A	C7H3BrN3NaO2	5 mg

• 4-AF DA
  A cell-permeable negative control compound for the nitric oxide (NO) fluorescent indicator DAF-2 DA (sc-221526). Unlike DAF-2 DA, 4-AF DA does not react with NO to form a fluorescent product.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-220924	N/A	C24H17NO7	1 mg

• 4-Amino-(6R)-5,6,7,8-tetrahydro-L-biopterin dihydrochloride

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-362202	N/A	C9H17N6O3 ·2HCl	10 mg

• 4-Chloro-3-methylpyridine 1-Oxide
  A nicotinamide analogue that acts as a neoplasm inhibitor.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-206857	1073-34-3	C6H6ClNO	10 mg

• 4-Methyl-1-hydrazinophthalizine Hydrochloride

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-216923	29902-28-1 (non-salt)	C9H10N4•HCl	10 mg

• 4-Phenyl-3-furoxancarbonitrile

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-206935	125520-62-9	C9H5N3O2	10 mg

• 5-Acetoxymethyl-2,3-dimethyl-4-chloropyridine N-oxide
  Intermediate in the preparation of Omeprazole metabolites

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-217113	N/A	C10H12ClNO3	10 mg

• 5-Acetoxymethyl-2,3-dimethylpyridine N-oxide
  Intermediate in the preparation of Omeprazole metabolites

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-217115	N/A	C10H13NO3	25 mg

• 7-Nitroindazole
  This product is a competitive, selective, and reversible specific neuronal nitric oxide synthase (NOS) inhibitor.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-3569	2942-42-9	C7H5N3O2	100 mg

• 7-Nitroindazole sodium salt
  Provides a useful tool for the study of nitric oxide (NO) activity in the brain. A more soluble salt form of 7-nitroindazole. Higher solubility in artificial cerebrospinal fluid (CSF) permits its use as an inhibitor of nitric oxide synthase (NOS) in rat brain tissue.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221114	2942-42-9 (non-salt)	C7H4N3O2 ·Na	5 mg/25 mg

• 7,8-Dihydro-L-biopterin
  BH2 is a precursor of BH4 synthesis. It is a noncompetitive inhibitor of GTP cyclohydrolase I.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202895	6779-87-9	C9H13N5O3	10 mg/50 mg

• α-Carboline-15N2 N-Oxide
  An intermediate in the preparation of labeled α-Carboline derivatives.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-220428	N/A	C11H8(15N)2O	1 mg

• α-Guanidinoglutaric acid
  Linear mixed-type inhibitor of neuronal nitric oxide synthase (nNOS/NOS I).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202031	73477-53-9	C6H11N3O4	10 mg/50 mg

• Agmatine sulfate
  The decarboxylated form of L-arginine. Binds α2-adrenergic receptors and imidazoline binding sites. Blocks NMDA receptor-associated ion channels. Inhibits NOS activity.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202920	2482-00-0	C5H14N4.H2SO4	100 mg/500 mg

• Aminoguanidine bicarbonate
  Inhibitor of nitric oxide synthase (NOS).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202460	2582-30-1	CH7N4 ·HCO3	100mg/500 mg

• Aminoguanidine hemisulfate
  An Inhibitor of NOS (nitric oxide synthase) and NO (nitric oxide).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202930	996-19-0	CH6N4 ·0.5H2SO4	100 mg/500 mg

• Aminoguanidine hydrochloride
  Irreversible inhibitor of iNOS that displays some selectivity over eNOS and nNOS.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202931	1937-19-5	CH6N4•HCl	100 mg/500 mg

• AMT HYDROCHLORIDE
  Potent, selective iNOS inhibitor

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202052	21463-31-0	C5H10N2S•HCl	10 mg/50 mg

• ARL 17477 dihydrochloride

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-361108	180983-17-9	C20H20ClN3S.2HCl	10 mg/50 mg

• Artemisinin
  Powerful antimalarial agent. Inhibits angiogenesis by down-regulating HIF-1α and VEGF expression. Inhibitor of human iNOS.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202960	63968-64-9	C15H22O5	100 mg/1 g

• BAY-41-8543
  Soluble guanylate cyclase (sGC) is the primary cellular receptor for nitric oxide (NO). NO binds and activates a heme group in sGC, initiating the conversion of GTP to the second messenger cyclic GMP (cGMP). BAY-41-8543 is a heme-dependent stimulator of sGC, increasing the activity of recombinant sGC dose-dependently up to 92-fold. Surprisingly, NO donors synergize with BAY-41-8543 in stimulating recombinant sGC. BAY-41-8543 relaxes vessels and inhibits platelet aggregation in vitro at nM concentrations. In vivo, BAY-41-8543 decreases blood pressure dose-dependently, prolongs bleeding time, and reduces thrombosis. Inhalation of microparticles containing BAY-41-8543 increases pulmonary vasodilation without changing mean arterial pressure suggesting that agonists of sGC may be efficacious in treating pulmonary hypertension.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-291927	256498-66-5	C21H21FN8O	1 mg/5 mg

• BEC, Hydrochloride
  A boronic acid-based arginine analog that acts as a slow-binding, competitive transition state inhibitor of arginases I and II (K = 310 nM for human recombinant type II arginase, pH 7.5). BEC does not inhibit nitric oxide synthase (NOS), it causes significant enhancement of NO-dependent smooth muscle relaxation in human penile corpus cavernosum tissue.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221291	N/A	C5H13BClNO4S	5 mg

• BYK 191023 dihydrochloride

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-361131	608880-48-4	C14H14N4O ·2HCl	10 mg/50 mg

• Canavanine sulfate
  A non-protein amino acid with structural analogy to L-arginine. Inhibits iNOS.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202983	2219-31-0	C5H12N4O3 ·H2SO4	100 mg/500 mg

• Carboxy-PTIO, potassium salt
  A stable nitric oxide radical scavenger that shows in chemical and biological systems antagonistic action against the free nitric oxide radical.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202985	148819-94-7	C14H16KN2O4	10 mg/50 mg

• Carboxy-PTIO, Sodium Salt
  Reacts with nitric oxide at pH 7.4, which results in the generation of NO2-/NO3--with a rate constant of 1 x 104 M-1 sec-1. It prevents SIN-1 induced endothelial cell death and has potent therapeutic value in endotoxin shock through its nitric oxide scavenging action.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221395	N/A	C14H16NaN2O4	10 mg

• D-NG-Nitroarginine Methyl Ester HCl (D-NAME)
  The inactive stereoisomer of L-NAME, employed as negative control in L-NAME-induced NOS inhibition studies.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-200335	50912-92-0	C7H15N5O4 ·HCl	200 mg/1 g

• DAF-FM
  An important quantitative reagent for low nitric oxide concentrations in solution. Upon reaction with nitric oxide, this product exhibits fluorescence.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221527	254109-20-1	C21H14F2N2O5	1 mg

• DAR-4M
  A rhodamine-based photo-stable nitric oxide (NO) fluorescent indicator with a detection limit of ~10 nM. Reacts with NO, in the presence of oxygen, resulting in a triazolo-rhodamine analog (DAR-4M T) that exhibits about 840-fold greater fluorescence quantum efficiency. The fluorescence intensity is not dependent on pH, unlike DAF-2.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221529	N/A	C25H26N4O3	1 mg

• DAR-4M AM
  A cell-permeable, photo-stable nitric oxide (NO) fluorescent indicator with a detection limit of ~10 nM. Intracellularly releases DAR-4M by the action of esterases. Reacts with NO, in the presence of oxygen, resulting in a triazolo-rhodamine analog (DAR-4M T) that exhibits about 840-fold greater fluorescence quantum efficiency. The fluorescence intensity is not dependent on pH.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221530	N/A	C28H31IN4O5	1 mg

• Diethylamine NONOate/AM
  An esterase-sensitive and cell permeable, O2-acetoxymethylated diazeniumdiolate that acts as an intracellular NO donor. Shown to induce apoptosis and to act as an antiproliferative agent in NO-sensitive human leukemia HL-60 and U937 cell lines. Also suppresses oxidized low-density lipoprotein-induced caspase-3 activation in bovine aortic endothelial cells. Exhibits enhanced stability in physiological buffers. May also be useful for temporal and spatial controlled NO availability.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221540	N/A	C7H15N3O4	1 mg/5 mg

• Diphenyleneiodonium chloride
  Binds strongly to flavoproteins. Powerful and specific inhibitor of several enzymes, including NOS, NADPH-ubiquinone oxidoreductase, NADPH oxidases and NADPH cytochrome P450 oxidoreductase.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202584	4673-26-1	C12H8ICl	25 mg/100 mg

• Diphenyleneiodonium Sulfate

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-207583	4510-83-2	C12H8I•1/2SO4	50 mg

• D-NG-Monomethylarginine (D-NMMA)
  An endothelin-derived relaxing factor inhibitor. Cell permeable. Negative control for NG-Monomethyl-L-arginine, L-NMMA (Cat. No. sc-200739).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-200332	137694-75-8	C7H16N4O2 ·CH3COOH	5 mg

• Ethylthiourea
  A compound most commonly used as a corrosion inhibitor for metals but also retains bactericidal properties. Used as a precursor for the synthesis of new rhenium complexes.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-203333	625-53-6	C3H8N2S	10 g

• FeTPPS
  A ferric porphyrin complex that catalytically isomerizes peroxynitrite to nitrate both in vivo and in vitro. Hence, serves as a decomposition catalyst and a selective peroxynitrite scavenger. Does not complex with nitric oxide and exhibits little SOD mimetic activity. Provides cytoprotection against peroxynitrite.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221611	90384-82-0	C44H28ClFeN4O12S4	25 mg

• Gallotannin
  Strongly inhibits NOS activity, endothelial constitutive NOS3 (eNOS; NOSIII), and PARG (poly (ADP-ribose) glycohydrolase).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202619	1401-55-4	C76H52O46	1 g/10 g

• GED bicarbonate
  Peroxynitrite scavenger. Potent inhibitor of mouse inducible nitric oxide synthase (iNOS; NOS II).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221664	N/A	N/A	10 mg

• Gemfibrozil
  A hyperlipidemic agent that elevates plasma HDL and lowers triglycerides and LDL by stabilizing apoA-I mRNA transcripts. It was found to inhibit inducible nitric oxide synthase by inhibiting the activation of nuclear factor-kappaB, activator protein-1 and CCAAT/enhancer-binding proein beta.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-204764	25812-30-0	C15H22O3	5 g/25 g

• Glyco-SNAP-1
  A water-soluble nitric oxide (NO) donor. More stable (t½ = 28.5-30.2 hr) than SNAP in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8 - 9). The SNAP moiety acts as an NO group donor and the sugar moiety provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes at a much slower rate in the presence of thiols such as glutathione or cysteine.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221680	188849-81-2	C13H23N3O8S	5 mg

• Histamine, Free Base
  A potent vasodilator found in normal tissues and blood; formed by the decarboxylation of L-histidine. Activates nitric oxide synthase (NOS), resulting in the release of nitric oxide.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-204000	51-45-6	C5H9N3	1 g/5 g

• Hydroxyurea-15N
  Anti-neoplastic with ribonucleoside reductase and DNA replication inhibitory effects. Potential therapy for sickle cell anemia involving the nitrosylation of sickle cell hemoglobin.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-207747	214331-53-0	CH4N2O2	1 mg

• Hyperforin dicyclohexylammonium salt
  An inhibitor of monoamine neurotransmitter uptake. Suppresses iNOS activity. Activates the TRPC6 receptor channel. Induces cytochrome p450 3A4 monooxygenase expression through activation of the pregnane X receptor.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202178	238074-03-8	C35H51O4•C12H24N	500 µg/1 mg

• Hypoestoxide, Hypoestes rosea
  A naturally occurring, cell-permeable diterpene with anti-inflammatory properties. A selective and direct IκB kinase inhibitor in TNF-α stimulated HeLa cells. This prevents NF-κB activation. Also inhibits the nitric oxide production by IL-1β or IL-17 stimulated chondrocytes.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221735	88498-46-8	C22H32O5	1 mg

• Isatin
  An endogenous monoamine oxidase inhibitor that is involved in stress and anxiety. This compound is an inhibitor of alkaline phosphatase, nitric oxide (NO)- stimulated soluble guanylate cyclase, and other enzymes.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-205721	91-56-5	C8H5NO2	100 g/500 g

• Isoniazid
  A front-line antituberculosis agent. Generates nitric oxide when activated by KatG. Also a strong inhibitor of DPH metabolism.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-205722	54-85-3	C6H7N3O	5 g/50 g

• L-Biopterin
  An obligate cofactor of inducible nitric oxide synthase.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-204781	22150-76-1	C9H11N5O3	25 mg/100 mg

• L-N6-(1-Iminoethyl) Lysine 5-Tetrazole Amide, Dihydrochloride

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-280886	N/A	C9H22Cl2N8O	5 mg

• L-NG-Monomethylarginine, Acetate Salt (L-NMMA)
  An inhibitor of Ca²⁺-dependent endothelial nitric oxide synthase. Also shown to increase leukocyte adherence and emigration and reduce venular shear rate in cat vascular endothelia.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-200739	53308-83-1	C9H20N4O4	25 mg

• L-NG-Nitroarginine Methyl Ester (L-NAME)
  A commonly used competitive and reversible inhibitor of NOS1, 2, and 3 which is more potent than L-NMMA (sc-200739).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-200333	51298-62-5	C7H15N5O4 ·HCl	1 g/5 g

• L-NIL, Dihydrochloride
  A potent inhibitor of nitric oxide synthase (NOS) that permeates the cell membrane.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-3567	150403-89-7	C8H17N3O2•2HCl	10 mg

• L-NIO dihydrochloride

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-361229	36889-13-1	C7H15N3O2.2HCl	10 mg/50 mg

• L-Sepiapterin
  Key intermediate in the pterin salvage pathway of tetrahydrobiopterin biosynthesis.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202689	17094-01-8	C9H11N5O3	10 mg/50 mg

• L-Thiocitrulline
  A potent inhibitor of Neuronal and Inducible Nitric Oxide Synthase.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221813	156719-37-8	C6H13N3O2S	10 mg/50 mg

• L-thiocitrulline, Dihydrochloride
  Potent stereospecific inhibitor of all three isoforms of rat nitric oxide synthases (NOS1,2, and 3), that demonstrates greater inhibitory activity on NOS1, compared to NOS2 or 3.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-3572	212051-53-1	C6H13N3O2S•2HCl	10 mg

• Lansoprazole-d4 Sulfone N-Oxide
  A labeled impurity of Lansoprazole.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-280903	N/A	C16H10F3N3O4S	1 mg

• Lipopolysaccharide, E. coli J5
  Mutant of E. coli O111: B4. It stimulates the activity of inducible nitric oxide synthase. It also induces apoptosis in mouse thymus and swine lymphocytes.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221854	N/A	N/A	5 mg

• Lipopolysaccharide, E. coli O55: B5
  This stimulates the activity of inducible nitric oxide synthase. It induces apoptosis in mouse thymus and swine lymphocytes.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221855	N/A	N/A	10 mg/25 mg

• Lipopolysaccharide, Salmonella minnesota Re 595
  This stimulates the activity of inducible nitric oxide synthase. It also induces apoptosis in mouse thymus and swine lymphocytes.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221856	N/A	N/A	5 mg

• Lipopolysaccharide, Ultra Pure, Salmonella minnesota R595 (Re)
  Phenol-petroleum ether extracted lipopolysaccharide (LPS) containing 0.3% proteins. LPS 595 (Re) has been shown to stimulate Toll-like receptor-4 (TLR4), but not TLR2, signaling in human cell lines.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221858	N/A	N/A	1 mg

• MEG sodium succinate
  Inhibits inducible nitric oxide synthase (iNOS; NOS II). Peroxynitrite scavenger.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221879	N/A	C3H10N3S•C4H4O4Na	10 mg

• MnTBAP chloride

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-221954	N/A	C48H28MnN4O8Cl	10 mg/50 mg

• N G-Nitro-L-arginine
  A potent nitric oxide synthase inhibitor with selectivity of NOS1 and NOS3 over NOS2.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-3570	2149-70-4	C6H13N5O4	1 g

• Glyco-SNAP-2
  A highly soluble nitric oxide donor, which is relatively stable at a high pH (pH 8-9).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-218911	188849-82-3	C13H23N3O8S	10 mg/50 mg

• N-(Dithiocarbamoyl)-N-Methyl-D-Glucamine, Sodium Salt
  A water soluble dithiocarbomate type chelator which is able to generate many transitional metal complexes. Useful for NO detection under physiological conditions.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-218966	91840-27-6	C8H16NNaO5S2	100 mg

• N-(Indole)nitroso Naratriptan
  A derivative of Naratriptan.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-218969	N/A	C17H24N4O3S	1 mg

• N-(Methyl-d3)-N'-nitrosopiperazine
  A labeled N-nitrosopiperazine derivative that displays strong nasal carcinogenicity and genotoxicity after low dose inhalation.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-218973	N/A	C5H8D3N3O	25 mg

• N-Benzylacetamidine Hydrobromide
  Of the different types of nitric oxide synthases (NOS), the inducible (iNOS) form contributes to inflammation and immune response while the constitutively-expressed endothelial (eNOS) enzyme plays important roles in regulating vascular tone. N-Benzylacetamidine is a potent inhibitor of iNOS (IC50 = 0.0 μM), with over 1,000-fold selectivity compared to eNOS (IC50 = 350 µM).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-295668	186545-76-6	C9H12N2•HBr	5 mg/10 mg

• N-Methyl-L-aspartic acid

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-212234	4226-18-0	C5H9NO4	10 mg/50 mg

• N-Nitroso Akardite II

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-219204	1076199-26-2	C14H13N3O2	250 mg

• N, N'G-Dimethyl-L-arginine di(p-hydroxyazobenzene-p'-sulfonate)
  Has been shown not to inhibit nitric oxide synthesis, both in vitro and in vivo. This salt form is more stable than the dihydrochloride.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202235	102783-24-4	C8H18N4O2 ·2C12H10N2O4S	5 mg/25 mg

• N,N-Dicarboxymethyl-N,N-dinitroso-p-phenylenediamine, Disodium Salt
  A caged, photolabile Nitric Oxide donor that is useful for delivering nitric oxide into intracellular compartments in microsecond time scale without any cytotoxic effects. Upon irradiation these donors produce two NO molecules per molecule of BNN.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-219273	1042969-16-3	C11H11N3Na2O5	1 mg

• N(5)-(1-Iminoethyl)-L-ornithine HCl (L-NIO)
  A potent inhibitor of endothelial cell nitric oxide synthase, neutrophil, and J774 enzymes. Also shown to induce a dose-dependent increase in mean systemic arterial blood pressure.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-200343	150403-88-6	C7H15N3O2 ·HCl	10 mg/100 mg

• NG-Amino-L-arginine hydrochloride
  Potent inhibitor of endothelial and inducible nitric oxide synthase (eNOS/NOS III and iNOS/NOS II).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-222066	N/A	C6H15N5O2•HCl	5 mg

• NG-Monoethyl-L-arginine . monoacetate

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-222068	N/A	C10H22N4O4	5 mg/25 mg

• NG-Monomethyl-L-homoarginine monoacetate

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-222069	N/A	C10H22N4O4	5 mg

• NG, N'G-Dimethyl-L-arginine dihydrochloride
  Does not inhibit nitric oxide synthesis, both in vitro and in vivo.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-222070	N/A	C8H18N4O2•2HCl	5 mg/25 mg

• N4-tert-Butoxycarbonyl-1-[2-(2-hydroxyethoxy)ethyl]piperazine N1-Oxide
  Intermediate in the preparation of Quetiapine derivatives.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-219313	N/A	C13H26N2O5	250 mg

• NG-Hydroxy-L-arginine, Monoacetate Salt
  Cell-permeable. A key intermediate in the biosynthesis of nitric oxide by constitutive nitric oxide synthase (cNOS). Can be efficiently oxidized to nitric oxide and citrulline by cytochrome P450 system.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-222067	53598-01-9	C6H14N4O3•CH3CO2H	25 mg/5 mg

• NG, NG-Dimethyl-L-arginine di(p-hydroxyazobenzene-p'-sulfonate)
  Inhibits nitric oxide synthesis. Also, the salt form is more stable than the dihydrochloride.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-224167	N/A	C32H38N8O10S2	5 mg/25 mg

• Nicotinic Acid Methyl Ester 5-N-Methylnitrone

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-219366	N/A	C9H10N2O3	100 mg

• Oleanolic Acid
  A naturally occurring triterpenoid found in garlic and Phytolacca Americana. Exhibits strong anti-HIV activity. Mechanism of action is the induction of iNOS and of Cyclooxygenase 2.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-205775	508-02-1	C30H48O3	100 mg/500 mg

• p-Nitroblue Tetrazolium Chloride
  NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase. Also displays activity as a scavenger of superoxide anions. Utilized as an alkaline phosphatase substrate.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-296003	298-83-9	C40H30Cl2N10O6	250 mg

• Penicillamine
  Exogenous NOS modulator, found to inhibit urease activity.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-205795	52-67-5	C5H11NO2S	1 g/5 g

• PTIO
  A stable radical species. Reacts with and extinguishes NO without affecting NOS activity.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202782	18390-00-6	C13H17N2O2	25 mg

• Ropinirole N-Oxide
  Reference standard.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-219988	1076199-41-1	C16H24N2O2	1 mg

• ROS Probe, HPF
  A cell-permeable, photo-stable hydroxyphenyl-substituted fluorescein compound that acts as a highly sensitive fluorescent probe for the detection of hydroxyl radical and peroxynitrite. It has little activity towards other reactive oxygen species (ROS), such as hypochlorite, singlet oxygen, superoxide, hydrogen peroxide, nitric oxide and alkyl peroxide.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-222262	359010-69-8	C26H16O6	1 mg

• S-(2-Aminoethyl)-ITU dihydrobromide
  Selective inhibitor of inducible nitric oxide synthase (iNOS/NOS II).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-202798	56-10-0	C3H9N3S. ·2HBr	10 mg/50 mg

• S-(3-Aminopropyl)-ITU dihydrobromide
  A Nitric oxide synthase (NOS) inhibitor. Selective for inducible nitric oxide synthase (iNOS/NOS II).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-205971	N/A	C4H15Br2N3S	10 mg/50 mg

• S-Ethyl N-[4-Triflurormethyl)phenyl]isothiourea, Hydrochloride
  A selective inhibitor of nNOS (NOS I) relative to iNOS (NOS II) (115-fold) and eNOS (NOS III) (29-fold). Also binds competitively with L-Arginine.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-208325	163490-78-6	C10H12ClF3N2S	10 mg

• S-Ethyl N-Phenylisothiourea
  A potent inhibitor of the human neuronal constitutive and inducible isoforms of nitric oxide synthetase. Demonstrates competitive binding with L-Arginine.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-208326	19801-34-4	C9H12N2S	50 mg

• S-Ethyl-N-[4-(trifluoromethyl)phenyl]isothiourea hydrochloride
  This is a selective inhibitor of neuronal nitric oxide synthase (nNOS; NOS I) which is relative to inducible nitric oxide synthase (iNOS; NOS II) (115-fold) and endothelial nitric oxide synthase (eNOS; NOS III) (29-fold).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-222274	N/A	C10H12ClF3N2S	5 mg/25 mg

• S-Ethylisothiourea HBr
  S-Ethylisothiourea is a potent iNOS competitive inhibitor with potential use in inflammatory and autoimmune disease therapy.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-200351	1071-37-0	C3H8N2S ·HBr	50 mg

• S-Isopropyl-ITU hydrobromide
  This is an inhibitor of nitric oxide synthase (NOS), and is 10 times more potent than S-Methyl-ITU.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-222276	4269-97-0	C4H10N2S•HBr	10 mg/50 mg

• S-Isopropylisothiourea hydrobromide
  Potent inhibitor of NO synthase, with selectivity for the inducible form.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-204252	57200-31-4	C4H10N2S.HBr	10 mg/50 mg

• S-Methyl-L thiocitrulline, Dihydrochloride
  Inhibitor of NOS that exhibits about 17-fold greater selectivity for rat NOS1 compared to NOS3.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-3571	156719-39-0	C7H15N3O2S•2HCl	10 mg

• S-Methyl-L-thiocitrulline acetate salt
  A potent inhibitor of inducible nitric oxide synthase with preference for constitutive (neuronal) over inducible (endothelial) NOS.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-215830	156719-41-4 (non-salt)	C9H19N3O4S	10 mg/50 mg

• S-Methylisothiourea Sulfate
  A potent and selective inhibitor of inducible NOS (iNOS).

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-3566	867-44-7	C4H14N4O4S3	100 mg

• S-Nitroso-N-heptanoyl-D,L-penicillamine
  Produced concentration-related relaxations of mouse anococcygeus, in a range similar to that already found for NO and other nitrovasodilators. A potent relaxant of non-vascular smooth muscle. Serves as an NO donor.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-220023	225234-00-4	C12H22N2O4S	10 mg

• S-Nitroso-N-propionyl-D,L-penicillamine
  Produced concentration-related relaxations of mouse anococcygeus, in a range similar to that already found for NO and other nitrovasodilators. A potent relaxant of non-vascular smooth muscle. Serves as an NO donor.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-220024	N/A	C8H14N2O4S	10 mg

• S-Nitroso-N-valeryl-D,L-penicillamine
  Exhibits higher lipophilicity and greater stability in solution than SNAP. Its decompostion is accelerated by the presence of Cu(II) and cysteine.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-220025	225233-99-8	C10H18N2O4S	25 mg

• S-Nitrosocaptopril
  This is an angiotensin-converting enzyme (ACE) inhibitor. It is an inhibitor of platelet aggregation. Its activity may depend on the homolytic cleavage of the S-N bond under physiological conditions, which yields nitric oxide (NO) and the parent compound, captopril.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-222277	122130-63-6	C9H14N2O4S	10 mg/50 mg

• Spermidine

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-215900	124-20-9	C7H19N3	1 g/5 g

• tert-Butyl N-[3-(Acetimidoylaminomethyl)benzyl]carbamate, Hydrochloride
  A long-acting human iNOS inhibitor possessing an IC₅₀ value of 2.0 μM. An intermediate for a selective inducible nitric oxide synthase (iNOS) inhibitor.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-208426	180001-98-3	C15H24ClN3O2	10 mg

• TRIM
  An inhibitor of nitric oxide synthase nNOS and iNOS with IC₅₀ values of 28.2 µM and 27.0 µM respectively.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-200353	25371-96-4	C10H7F3N2	100 mg/500 mg

• Troleandomycin
  A macrolide antibiotic that is a stronger inhibitor than Roxithromycin (sc-205845). Inhibits P450 and has been used in multiple asthma studies.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-200747	2751-09-9	C41H67NO15	10 mg/50 mg

• Vinyl-L-NIO
  Very selective and potent neuronal nitric oxide synthase (nNOS/NOS I) inhibitor.

  Codice del prodotto	CAS Number	Molecular Formula	Unità
  sc-222412	728944-69-2	C9H17N3O2 ·2HCl	5 mg/25 mg